Dicer is required for maintenance of adult pancreatic acinar cell identity and plays a role in Kras-driven pancreatic neoplasia.

The role of miRNA processing in the maintenance of adult pancreatic acinar cell identity and during the initiation and progression of pancreatic neoplasia has not been studied in detail. In this work, we deleted Dicer specifically in adult pancreatic acinar cells, with or without simultaneous activa...

Full description

Bibliographic Details
Main Authors: Yue J Wang, Florencia McAllister, Jennifer M Bailey, Sherri-Gae Scott, Audrey M Hendley, Steven D Leach, Bidyut Ghosh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4236134?pdf=render