Ethers and esters derived from apocynin avoid the interaction between p47phox and p22phox subunits of NADPH oxidase: evaluation in vitro and in silico
NOX (NADPH oxidase) plays an important role during several pathologies because it produces the superoxide anion (O2•−), which reacts with NO (nitric oxide), diminishing its vasodilator effect. Although different isoforms of NOX are expressed in ECs (endothelial cells) of blood...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Portland Press, Biochemical Society
2013-08-01
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Series: | Bioscience Reports |
Subjects: | |
Online Access: | http://www.bioscirep.org/bsr/033/e055/bsr033e055.htm |