Generation and characterization of iPSC-derived renal proximal tubule-like cells with extended stability

Generation and characterization of iPSC-derived renal proximal tubule-like cells with extended stability

Abstract The renal proximal tubule is responsible for re-absorption of the majority of the glomerular filtrate and its proper function is necessary for whole-body homeostasis. Aging, certain diseases and chemical-induced toxicity are factors that contribute to proximal tubule injury and chronic kidn...

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Main Authors: Vidya Chandrasekaran, Giada Carta, Daniel da Costa Pereira, Rajinder Gupta, Cormac Murphy, Elisabeth Feifel, Georg Kern, Judith Lechner, Anna Lina Cavallo, Shailesh Gupta, Florian Caiment, Jos C. S. Kleinjans, Gerhard Gstraunthaler, Paul Jennings, Anja Wilmes
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-89550-4

Internet

https://doi.org/10.1038/s41598-021-89550-4

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