Rift Valley Fever Vaccine Virus Clone 13 Is Able to Cross the Ovine Placental Barrier Associated with Foetal Infections, Malformations, and Stillbirths.

Rift Valley fever virus (RVFV) is a mosquito-borne pathogen that affects domesticated ruminants and occasionally humans. Classical RVF vaccines are based on formalin-inactivated virus or the live-attenuated Smithburn strain. The inactivated vaccine is highly safe but requires multiple administration...

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Bibliographic Details
Main Authors: Birgit Makoschey, Emma van Kilsdonk, Willem R Hubers, Mieke P Vrijenhoek, Marianne Smit, Paul J Wichgers Schreur, Jeroen Kortekaas, Véronique Moulin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-03-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4816553?pdf=render