Complete Loss of EPCAM Immunoexpression Identifies <i>EPCAM</i> Deletion Carriers in MSH2-Negative Colorectal Neoplasia

Complete Loss of EPCAM Immunoexpression Identifies <i>EPCAM</i> Deletion Carriers in MSH2-Negative Colorectal Neoplasia

The use of epithelial cell adhesion molecule (EPCAM) immunohistochemistry (IHC) is not included in the colorectal cancer (CRC) screening algorithm to detect Lynch syndrome (LS) patients. The aim of the present study was to demonstrate that EPCAM IHC is a useful tool to guide the LS germ-line analysi...

Full description

Bibliographic Details
Main Authors: Míriam Cuatrecasas, Iñigo Gorostiaga, Cristina Riera, Esteban Saperas, Gemma Llort, Irmgard Costa, Xavier Matias-Guiu, Cristina Carrato, Matilde Navarro, Marta Pineda, Núria Dueñas, Joan Brunet, Vicente Marco, Isabel Trias, José Ignacio Busteros, Gemma Mateu, Francesc Balaguer, María-Teresa Fernández-Figueras, Manel Esteller, Eva Musulén
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
lynch syndrome
<i>EPCAM</i>
immunohistochemistry
colorectal cancer
colon polyps
Online Access:https://www.mdpi.com/2072-6694/12/10/2803

Internet

https://www.mdpi.com/2072-6694/12/10/2803

Similar Items