GSK3β-dependent phosphorylation alters DNA binding, transactivity and half-life of the transcription factor USF2.

The upstream stimulatory factor 2 (USF2) is a regulator of important cellular processes and is supposed to have also a role during tumor development. However, the knowledge about the mechanisms that control the function of USF2 is limited. The data of the current study show that USF2 function is reg...

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Bibliographic Details
Main Authors: Tina Horbach, Tabughang Franklin Chi, Claudia Götz, Satyan Sharma, André H Juffer, Elitsa Y Dimova, Thomas Kietzmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4169611?pdf=render