Control of whole heart geometry by intramyocardial mechano-feedback: a model study.

Geometry of the heart adapts to mechanical load, imposed by pressures and volumes of the cavities. We regarded preservation of cardiac geometry as a homeostatic control system. The control loop was simulated by a chain of models, starting with geometry of the cardiac walls, sequentially simulating c...

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Bibliographic Details
Main Authors: Theo Arts, Joost Lumens, Wilco Kroon, Tammo Delhaas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-02-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3276542?pdf=render