Detecting methylation signatures in neurodegenerative disease by density-based clustering of applications with reducing noise

Abstract There have been numerous genetic and epigenetic datasets generated for the study of complex disease including neurodegenerative disease. However, analysis of such data often suffers from detecting the outliers of the samples, which subsequently affects the extraction of the true biological...

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Bibliographic Details
Main Authors: Saurav Mallik, Zhongming Zhao
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-78463-3