VEGF Maintains Maternal Vascular Space Homeostasis in the Mouse Placenta through Modulation of Trophoblast Giant Cell Functions

Vascular endothelial growth factor (VEGF) is an angiogenic growth factor that acts primarily on endothelial cells, but numerous studies suggest that VEGF also acts on non-endothelial cells, including trophoblast cells. Inhibition of VEGF signaling by excess production of the endogenous soluble VEGF...

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Bibliographic Details
Main Authors: Xiujun Fan, Shanmugam Muruganandan, Philemon D Shallie, Sabita Dhal, Matthew Petitt, Nihar R Nayak
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Biomolecules
Subjects:
TGC
Online Access:https://www.mdpi.com/2218-273X/11/7/1062