Detecting Variants in the NBN Gene While Testing for Hereditary Breast Cancer: What to Do Next?

Detecting Variants in the NBN Gene While Testing for Hereditary Breast Cancer: What to Do Next?

The NBN gene has been included in breast cancer (BC) multigene panels based on early studies suggesting an increased BC risk for carriers, though not confirmed by recent research. To evaluate the impact of NBN analysis, we assessed the results of NBN sequencing in 116 BRCA-negative BC patients and r...

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Bibliographic Details
Main Authors: Roberta Zuntini, Elena Bonora, Laura Maria Pradella, Laura Benedetta Amato, Michele Vidone, Sara De Fanti, Irene Catucci, Laura Cortesi, Veronica Medici, Simona Ferrari, Giuseppe Gasparre, Paolo Peterlongo, Marco Sazzini, Daniela Turchetti
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
hereditary breast cancer
NBN
nibrin
variants
Online Access:https://www.mdpi.com/1422-0067/22/11/5832

Internet

https://www.mdpi.com/1422-0067/22/11/5832

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