<i>NPM1</i>-Mutated Myeloid Neoplasms with <20% Blasts: A Really Distinct Clinico-Pathologic Entity?

<i>NPM1</i>-Mutated Myeloid Neoplasms with <20% Blasts: A Really Distinct Clinico-Pathologic Entity?

Nucleophosmin (<i>NPM1</i>) gene mutations rarely occur in non-acute myeloid neoplasms (MNs) with <20% blasts. Among nearly 10,000 patients investigated so far, molecular analyses documented <i>NPM1</i> mutations in around 2% of myelodysplastic syndrome (MDS) cases, mainly...

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Bibliographic Details
Main Authors: Fabio Forghieri, Vincenzo Nasillo, Ambra Paolini, Francesca Bettelli, Valeria Pioli, Davide Giusti, Andrea Gilioli, Corrado Colasante, Gloria Acquaviva, Giovanni Riva, Patrizia Barozzi, Rossana Maffei, Leonardo Potenza, Roberto Marasca, Claudio Fozza, Enrico Tagliafico, Tommaso Trenti, Patrizia Comoli, Giuseppe Longo, Mario Luppi
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
<i>NPM1</i> mutation
myelodysplastic syndromes
myelodysplastic/myeloproliferative neoplasms
chronic myelomonocytic leukemia
acute myeloid leukemia
leukemogenesis
Online Access:https://www.mdpi.com/1422-0067/21/23/8975

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https://www.mdpi.com/1422-0067/21/23/8975

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