Lamin Mutations Cause Increased YAP Nuclear Entry in Muscle Stem Cells

Lamin Mutations Cause Increased YAP Nuclear Entry in Muscle Stem Cells

Mutations in the <i>LMNA</i> gene, encoding the nuclear envelope A-type lamins, are responsible for muscular dystrophies, the most severe form being the <i>LMNA</i>-related congenital muscular dystrophy (L-CMD), with severe defects in myonucleus integrity. We previously repor...

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Bibliographic Details
Main Authors: Daniel J. Owens, Martina Fischer, Saline Jabre, Sophie Moog, Kamel Mamchaoui, Gillian Butler-Browne, Catherine Coirault
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cells
Subjects:
lamins
congenital myopathy
nucleo-cytoskeletal translocation
nuclear envelope
Online Access:https://www.mdpi.com/2073-4409/9/4/816

Internet

https://www.mdpi.com/2073-4409/9/4/816

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