Galectin-8 Favors the Presentation of Surface-Tethered Antigens by Stabilizing the B Cell Immune Synapse

Galectin-8 Favors the Presentation of Surface-Tethered Antigens by Stabilizing the B Cell Immune Synapse

Summary: Complete activation of B cells relies on their capacity to extract tethered antigens from immune synapses by either exerting mechanical forces or promoting their proteolytic degradation through lysosome secretion. Whether antigen extraction can also be tuned by local cues originating from t...

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Bibliographic Details
Main Authors: Dorian Obino, Luc Fetler, Andrea Soza, Odile Malbec, Juan José Saez, Mariana Labarca, Claudia Oyanadel, Felipe Del Valle Batalla, Nicolas Goles, Aleksandra Chikina, Danielle Lankar, Fabián Segovia-Miranda, Camille Garcia, Thibaut Léger, Alfonso Gonzalez, Marion Espéli, Ana-Maria Lennon-Duménil, Maria-Isabel Yuseff
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718318151

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http://www.sciencedirect.com/science/article/pii/S2211124718318151

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