Repulsive cues combined with physical barriers and cell–cell adhesion determine progenitor cell positioning during organogenesis

Repulsive cues combined with physical barriers and cell–cell adhesion determine progenitor cell positioning during organogenesis

The precise positioning of organ progenitor cells is essential for organ development and function. Here the authors use live imaging and mathematical modelling to show that the confinement of a motile progenitor cell population results from coupled physical barriers and cell-cell interactions.

Bibliographic Details
Main Authors: Azadeh Paksa, Jan Bandemer, Burkhard Hoeckendorf, Nitzan Razin, Katsiaryna Tarbashevich, Sofia Minina, Dana Meyen, Antonio Biundo, Sebastian A. Leidel, Nadine Peyrieras, Nir S. Gov, Philipp J. Keller, Erez Raz
Format: Article
Language:English
Published: Nature Publishing Group 2016-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11288

Internet

https://doi.org/10.1038/ncomms11288

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