Crystal Structure, Stability and Desolvation of the Solvates of Sorafenib Tosylate

In this study, three solvates of sorafenib tosylate were obtained from methanol, ethanol and n-methyl-2-pyrrolidone (NMP) after solvate screening and the effect of solvent on the formation of solvate was analyzed. The solvents with high value of polarity/dipolarity and appropriate hydrogen bond dono...

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Bibliographic Details
Main Authors: Peng Yang, Chunlei Qin, Shichao Du, Lina Jia, Yujia Qin, Junbo Gong, Songgu Wu
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Crystals
Subjects:
Online Access:https://www.mdpi.com/2073-4352/9/7/367