EZH2 Single Nucleotide Variants (SNVs): Diagnostic and Prognostic Role in 10 Solid Tumor Types

The enhancer of zeste homolog 2 (EZH2) gene encodes a histone methyltransferase that is a catalytic subunit of the Polycomb repressive complex 2 (PRC2) group of proteins that act to repress gene expression. The EZH2 locus is rarely mutated in solid tumors and there is no comprehensive study of EZH2...

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Bibliographic Details
Main Authors: Elisa Paolicchi, Lorenzo Fornaro, Stefano Landi, Sushilaben Rigas, Francesco Crea
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Epigenomes
Subjects:
Online Access:https://www.mdpi.com/2075-4655/1/3/18