Designed Chemical Intervention with Thiols for Prophylactic Contraception.

Designed Chemical Intervention with Thiols for Prophylactic Contraception.

Unlike somatic cells, sperm have several-fold more available-thiols that are susceptible to redox-active agents. The present study explains the mechanism behind the instant sperm-immobilizing and trichomonacidal activities of pyrrolidinium pyrrolidine-1-carbodithioate (PPC), a novel thiol agent rati...

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Bibliographic Details
Main Authors: Monika Sharma, Lokesh Kumar, Ashish Jain, Vikas Verma, Vikas Sharma, Bhavana Kushwaha, Nand Lal, Lalit Kumar, Tara Rawat, Anil K Dwivedi, Jagdamba P Maikhuri, Vishnu L Sharma, Gopal Gupta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3694959?pdf=render

Internet

http://europepmc.org/articles/PMC3694959?pdf=render

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