<i>SRSF2</i> Mutations in Uveal Melanoma: A Preference for In-Frame Deletions?

<i>Background:</i> Uveal melanoma (UM) is the most common primary ocular malignancy in adults in the Western world. UM with a mutation in <i>SF3B1</i>, a spliceosome gene, is characterized by three or more structural changes of chromosome 1, 6, 8, 9, or 11. Also UM without a...

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Bibliographic Details
Main Authors: Natasha M. van Poppelen, Wojtek Drabarek, Kyra N. Smit, Jolanda Vaarwater, Tom Brands, Dion Paridaens, Emine Kiliç, Annelies de Klein
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/11/8/1200