High throughput determination of TGFβ1/SMAD3 targets in A549 lung epithelial cells.

High throughput determination of TGFβ1/SMAD3 targets in A549 lung epithelial cells.

<h4>Background</h4>Transforming growth factor beta 1 (TGFβ1) plays a major role in many lung diseases including lung cancer, pulmonary hypertension, and pulmonary fibrosis. TGFβ1 activates a signal transduction cascade that results in the transcriptional regulation of genes in the nucleu...

Full description

Bibliographic Details
Main Authors: Yingze Zhang, Daniel Handley, Tommy Kaplan, Haiying Yu, Abha S Bais, Thomas Richards, Kusum V Pandit, Qilu Zeng, Panayiotis V Benos, Nir Friedman, Oliver Eickelberg, Naftali Kaminski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21625455/pdf/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21625455/pdf/?tool=EBI

Similar Items