The role of Galectin-3 in modulating tumor growth and immunosuppression within the tumor microenvironment

The efficacy of cancer immunotherapy is limited, in part, by the multitude of immunosuppressive mechanisms present within the tumor microenvironment (TME). Galectin-3 (Gal-3) is a lectin that contributes to TME immunosuppression and regulates diverse functions including cellular homeostasis and canc...

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Bibliographic Details
Main Authors: Mohammad Farhad, Annah S. Rolig, William L. Redmond
Format: Article
Language:English
Published: Taylor & Francis Group 2018-06-01
Series:OncoImmunology
Subjects:
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1434467