Specific O-GlcNAc modification at Ser-615 modulates eNOS function

Specific O-GlcNAc modification at Ser-615 modulates eNOS function

Idiopathic pulmonary arterial hypertension (IPAH) is a progressive and devastating disease characterized by vascular smooth muscle and endothelial cell proliferation leading to a narrowing of the vessels in the lung. The increased resistance in the lung and the higher pressures generated result in r...

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Bibliographic Details
Main Authors: Kulwant S. Aulak, Jarrod W. Barnes, Liping Tian, Noel E. Mellor, Mohammad M. Haque, Belinda Willard, Ling Li, Suzy C. Comhair, Dennis J. Stuehr, Raed A. Dweik
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Redox Biology
Subjects:
Endothelial nitric oxide synthetase
O-GlcNAc modification
Pulmonary arterial hypertension
Nitric oxide
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720308302

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http://www.sciencedirect.com/science/article/pii/S2213231720308302

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