Allogeneic cardiospheres delivered via percutaneous transendocardial injection increase viable myocardium, decrease scar size, and attenuate cardiac dilatation in porcine ischemic cardiomyopathy.

Allogeneic cardiospheres delivered via percutaneous transendocardial injection increase viable myocardium, decrease scar size, and attenuate cardiac dilatation in porcine ischemic cardiomyopathy.

<h4>Background</h4>Epicardial injection of heart-derived cell products is safe and effective post-myocardial infarction (MI), but clinically-translatable transendocardial injection has never been evaluated. We sought to assess the feasibility, safety and efficacy of percutaneous transend...

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Bibliographic Details
Main Authors: Kristine Yee, Konstantinos Malliaras, Hideaki Kanazawa, Eleni Tseliou, Ke Cheng, Daniel J Luthringer, Chak-Sum Ho, Kentaro Takayama, Naoto Minamino, James F Dawkins, Supurna Chowdhury, Doan Trang Duong, Jeffrey Seinfeld, Ryan C Middleton, Rohan Dharmakumar, Debiao Li, Linda Marbán, Raj R Makkar, Eduardo Marbán
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0113805

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https://doi.org/10.1371/journal.pone.0113805

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