Deciphering human cell-autonomous anti-HSV-1 immunity in the central nervous system

Deciphering human cell-autonomous anti-HSV-1 immunity in the central nervous system

Herpes Simplex Virus-1 (HSV-1) is a common virus that can rarely invade the human central nervous system (CNS), causing devastating encephalitis. The permissiveness to HSV-1 of the various relevant cell types involved in the disease, neurons, astrocytes, oligodendrocytes and microglia cells, as well...

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Bibliographic Details
Main Authors: Fabien Gilbert Lafaille, Michael eCiancaneli, Jean-Laurent eCasanova, Shen-Ying eZhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Immunology
Subjects:
Astrocytes
Interferons
Neurons
HSV-1
TLR3
CNS
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00208/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00208/full

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