Pioglitazone Represents an Effective Therapeutic Target in Preventing Oxidative/Inflammatory Cochlear Damage Induced by Noise Exposure

Pioglitazone Represents an Effective Therapeutic Target in Preventing Oxidative/Inflammatory Cochlear Damage Induced by Noise Exposure

Recent progress in hearing loss research has provided strong evidence for the imbalance of cellular redox status and inflammation as common predominant mechanisms of damage affecting the organ of Corti including noise induced hearing loss. The discovery of a protective molecule acting on both mechan...

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Bibliographic Details
Main Authors: Fabiola Paciello, Anna Rita Fetoni, Rolando Rolesi, Matthew B. Wright, Claudio Grassi, Diana Troiani, Gaetano Paludetti
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Pharmacology
Subjects:
PPAR agonist
acoustic trauma
antioxidant
antinflammatory
audiology
personalized medicine
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01103/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.01103/full

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