Bipolar filaments of human nonmuscle myosin 2-A and 2-B have distinct motile and mechanical properties

Bipolar filaments of human nonmuscle myosin 2-A and 2-B have distinct motile and mechanical properties

Nonmusclemyosin 2 (NM-2) powers cell motility and tissue morphogenesis by assembling into bipolar filaments that interact with actin. Although the enzymatic properties of purified NM-2 motor fragments have been determined, the emergent properties of filament ensembles are unknown. Using single myosi...

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Bibliographic Details
Main Authors: Luca Melli, Neil Billington, Sara A Sun, Jonathan E Bird, Attila Nagy, Thomas B Friedman, Yasuharu Takagi, James R Sellers
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-02-01
Series:eLife
Subjects:
myosin
actin
motility
mechanochemistry
Online Access:https://elifesciences.org/articles/32871

Internet

https://elifesciences.org/articles/32871

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