TNFR1 and TNFR2 Expression and Induction on Human Treg Cells from Type 1 Diabetic Subjects

TNFR1 and TNFR2 Expression and Induction on Human Treg Cells from Type 1 Diabetic Subjects

Several autoimmune diseases are marked by a deficiency of soluble tumor necrosis factor (TNF). The TNF deficiency is caused in at least one autoimmune disease, multiple sclerosis, by an overabundance of TNF receptor 1 (TNFR1). Excess TNFR1 binds and inactivates TNF and this leaves less TNF bioavaila...

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Bibliographic Details
Main Authors: Melanie Heinrich, Douglas Burger, Limei Wang, Georges Tahhan, Peter Reinhold, Menghan Zhao, Elise Hsu, Sarah Warden, Danielle Baum, Denise L Faustman
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:Antibodies
Subjects:
TNFR2
type 1 diabetes
autoimmunity
T regulatory cells (Treg)
Online Access:http://www.mdpi.com/2073-4468/4/1/34

Internet

http://www.mdpi.com/2073-4468/4/1/34

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