GSK3β inhibitor promotes myelination and mitigates muscle atrophy after peripheral nerve injury

GSK3β inhibitor promotes myelination and mitigates muscle atrophy after peripheral nerve injury

Delay of axon regeneration after peripheral nerve injury usually leads to progressive muscle atrophy and poor functional recovery. The Wnt/β-catenin signaling pathway is considered to be one of the main molecular mechanisms that lead to skeletal muscle atrophy in the elderly. We hold the hypothesis...

Full description

Bibliographic Details
Main Authors: Jian Weng, Yan-hua Wang, Ming Li, Dian-ying Zhang, Bao-guo Jiang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; glycogen synthase kinase 3 beta inhibitor; SB216763; myelination; myotube differentiation; denervated muscle atrophy; Wnt/β-catenin; Schwann cell; muscle cells; peripheral nerve injury; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2018;volume=13;issue=2;spage=324;epage=330;aulast=Weng

Internet

http://www.nrronline.org/article.asp?issn=1673-5374;year=2018;volume=13;issue=2;spage=324;epage=330;aulast=Weng

Similar Items