Genetic Etiologies for Phenotypic Diversity in Sickle Cell Anemia
The clinical course of patients with sickle cell anemia, a Mendelian trait, is characteristically highly variable. HbF concentration and the presence of a thalassemia are established modulators of the disease, but cannot account for all of its clinical heterogeneity. To find additional genetic modul...
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| Format: | Article |
| Language: | English |
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Hindawi Limited
2009-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/tsw.2009.10 |