Aminoguanidine inhibits aortic hydrogen peroxide production, VSMC NOX activity and hypercontractility in diabetic mice

<p>Abstract</p> <p>Background</p> <p>Dysfunctionally uncoupled endothelial nitric oxide synthase (eNOS) is involved in producing reactive oxygen species (ROS) in the diabetic endothelium. The present study investigated whether anti-diabetes drug Aminoguanidine (AG) has...

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Bibliographic Details
Main Authors: Youn Ji-Youn, Oak Jeong-Ho, Cai Hua
Format: Article
Language:English
Published: BMC 2009-12-01
Series:Cardiovascular Diabetology
Online Access:http://www.cardiab.com/content/8/1/65