Absence of the TAP2 human recombination hotspot in chimpanzees.

Recent experiments using sperm typing have demonstrated that, in several regions of the human genome, recombination does not occur uniformly but instead is concentrated in "hotspots" of 1-2 kb. Moreover, the crossover asymmetry observed in a subset of these has led to the suggestion that h...

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Bibliographic Details
Main Authors: Susan E Ptak, Amy D Roeder, Matthew Stephens, Yoav Gilad, Svante Pääbo, Molly Przeworski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2004-06-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC423135?pdf=render