Amino Acid Deletions in p6<sup>Gag</sup> Domain of HIV-1 CRF07_BC Ameliorate Galectin-3 Mediated Enhancement in Viral Budding

Amino Acid Deletions in p6<sup>Gag</sup> Domain of HIV-1 CRF07_BC Ameliorate Galectin-3 Mediated Enhancement in Viral Budding

HIV-1 CRF07_BC is a recombinant virus with amino acid (a.a.) deletions in p6<sup>Gag</sup>, which are overlapped with the Alix-binding domain. Galectin-3 (Gal3), a β-galactose binding lectin, has been reported to interact with Alix and regulate HIV-1 subtype B budding. This study aims to...

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Bibliographic Details
Main Authors: Wen-Hung Wang, Chun-Sheng Yeh, Chih-Yen Lin, Ruei-Yu Yuan, Aspiro Nayim Urbina, Po-Liang Lu, Yen-Hsu Chen, Yi-Ming Arthur Chen, Fu-Tong Liu, Sheng-Fan Wang
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
Galectin-3
HIV-1
CRF07_BC
p6<sup>Gag</sup>
Alix
Online Access:https://www.mdpi.com/1422-0067/21/8/2910

Internet

https://www.mdpi.com/1422-0067/21/8/2910

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