Characterization of Redox-Responsive LXR-Activating Nanoparticle Formulations in Primary Mouse Macrophages

Characterization of Redox-Responsive LXR-Activating Nanoparticle Formulations in Primary Mouse Macrophages

Activation of the transcription factor liver X receptor (LXR) has beneficial effects on macrophage lipid metabolism and inflammation, making it a potential candidate for therapeutic targeting in cardiometabolic disease. While small molecule delivery via nanomedicine has promising applications for a...

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Bibliographic Details
Main Authors: Tyler K. T. Smith, Zaina Kahiel, Nicholas D. LeBlond, Peyman Ghorbani, Eliya Farah, Refel Al-Awosi, Marceline Cote, Suresh Gadde, Morgan D. Fullerton
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Molecules
Subjects:
nanomedicine
nanoparticles
drug delivery
lxr agonists
abca1
macrophages
redox-responsive nanoparticle
Online Access:https://www.mdpi.com/1420-3049/24/20/3751

Internet

https://www.mdpi.com/1420-3049/24/20/3751

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