<i>Helicobacter pylori</i> CagA Induces Cortactin Y-470 Phosphorylation-Dependent Gastric Epithelial Cell Scattering via Abl, Vav2 and Rac1 Activation

<i>Helicobacter pylori</i> CagA Induces Cortactin Y-470 Phosphorylation-Dependent Gastric Epithelial Cell Scattering via Abl, Vav2 and Rac1 Activation

The pathogen <i>Helicobacter pylori</i> is the first reported bacterial type-1 carcinogen playing a role in the development of human malignancies, including gastric adenocarcinoma. Cancer cell motility is an important process in this scenario, however, the molecular mechanisms are still...

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Bibliographic Details
Main Authors: Nicole Tegtmeyer, Aileen Harrer, Klemens Rottner, Steffen Backert
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
<i>Helicobacter</i>
cancer
cortactin
pathogenesis
pathogenicity island
signaling
Online Access:https://www.mdpi.com/2072-6694/13/16/4241

Internet

https://www.mdpi.com/2072-6694/13/16/4241

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