Dopamine and pain sensitivity: neither sulpiride nor acute phenylalanine and tyrosine depletion have effects on thermal pain sensations in healthy volunteers.

Dopamine and pain sensitivity: neither sulpiride nor acute phenylalanine and tyrosine depletion have effects on thermal pain sensations in healthy volunteers.

Based on animal studies and some indirect clinical evidence, dopamine has been suggested to have anti-nociceptive effects. Here, we investigated directly the effects of increased and decreased availability of extracellular dopamine on pain perception in healthy volunteers. In Study 1, participants i...

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Bibliographic Details
Main Authors: Susanne Becker, Marta Ceko, Mytsumi Louis-Foster, Nathaniel M Elfassy, Marco Leyton, Yoram Shir, Petra Schweinhardt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3827462?pdf=render

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http://europepmc.org/articles/PMC3827462?pdf=render

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