Characterizing the Relationship Between Neutralization Sensitivity and env Gene Diversity During ART Suppression

Characterizing the Relationship Between Neutralization Sensitivity and env Gene Diversity During ART Suppression

Although antiretroviral therapy (ART) successfully suppresses HIV-1 replication, ART-treated individuals must maintain therapy to avoid rebound from an integrated viral reservoir. Strategies to limit or clear this reservoir are urgently needed. Individuals infected for longer periods prior to ART ap...

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Bibliographic Details
Main Authors: Andrew Wilson, Leyn Shakhtour, Adam Ward, Yanqin Ren, Melina Recarey, Eva Stevenson, Maria Korom, Colin Kovacs, Erika Benko, R. Brad Jones, Rebecca M. Lynch
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
broadly neutralizing antibodies
HIV-1
diversity
env gene
autologous antibodies
ART suppression
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.710327/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.710327/full

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