Optimization of DNA delivery by three classes of hybrid nanoparticle/DNA complexes

<p>Abstract</p> <p>Plasmid DNA encoding a luciferase reporter gene was complexed with each of six different hybrid nanoparticles (NPs) synthesized from mixtures of poly (D, L-lactide-co-glycolide acid) (PLGA 50:50) and the cationic lipids DOTAP (1, 2-Dioleoyl-3-Trimethyammonium-Pro...

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Bibliographic Details
Main Authors: Mandal Tarun K, Yao Xin, Wang Haifan, Pamujula Sarala, Chinta Dakshina, Zhong Qiu, Luftig Ronald B
Format: Article
Language:English
Published: BMC 2010-02-01
Series:Journal of Nanobiotechnology
Online Access:http://www.jnanobiotechnology.com/content/8/1/6