Effect on Nail Structure and Transungual Permeability of the Ethanol and Poloxamer Ratio from Cyclodextrin-Soluble Polypseudorotaxanes Based Nail Lacquer

Effect on Nail Structure and Transungual Permeability of the Ethanol and Poloxamer Ratio from Cyclodextrin-Soluble Polypseudorotaxanes Based Nail Lacquer

Aqueous-based nail lacquers have shown potential in promoting the diffusion of drugs into the nail. In our laboratory, we have recently developed a transungual delivery system based on an aqueous dispersion of cyclodextrin-poloxamer soluble polypseudorotaxanes, supramolecular host−guest as...

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Bibliographic Details
Main Authors: Elena Cutrín-Gómez, Soledad Anguiano-Igea, M. Begoña Delgado-Charro, José Luis Gómez-Amoza, Francisco J. Otero-Espinar
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Pharmaceutics
Subjects:
transungual drug delivery
nail
medicated nail lacquers
onychomycosis
nail psoriasis ungueal
polypseudorotaxanes
methyl-β-cyclodextrin
poloxamers
ciclopirox olamine
clobetasol propionate
Online Access:http://www.mdpi.com/1999-4923/10/3/156

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http://www.mdpi.com/1999-4923/10/3/156

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