HIV induces synaptic hyperexcitation via cGMP-dependent protein kinase II activation in the FIV infection model.
Over half of individuals infected with human immunodeficiency virus (HIV) suffer from HIV-associated neurocognitive disorders (HANDs), yet the molecular mechanisms leading to neuronal dysfunction are poorly understood. Feline immunodeficiency virus (FIV) naturally infects cats and shares its structu...
Main Authors: | , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-07-01
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Series: | PLoS Biology |
Online Access: | http://europepmc.org/articles/PMC6082575?pdf=render |