Lipotoxicity is glucose-dependent in INS-1E cells but not in human islets and MIN6 cells
<p>Abstract</p> <p>Background</p> <p>Prolonged elevated levels of lipids have negative effects on beta-cell function and mass (lipotoxicity). To what extent exposure to high glucose concentration is important in the harmful effects of lipids (glucolipotoxicity) has been...
Main Authors: | Bergsten Peter, Sargsyan Ernest |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-07-01
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Series: | Lipids in Health and Disease |
Subjects: | |
Online Access: | http://www.lipidworld.com/content/10/1/115 |
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