Transplacental RNAi: Deciphering Gene Function in the Postimplantation-Staged Embryo

RNAi offers the opportunity to examine the role in postimplantation development of genes that cause preimplantation lethality and to create allelic series of targeted embryos. We have delivered constituitively expressed short hairpin (sh) RNAs to pregnant mice during the early postimplantation perio...

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Bibliographic Details
Main Authors: K. Sue O'Shea, Lisa S. De Boer, Nicole A. Slawny, Theresa E. Gratsch
Format: Article
Language:English
Published: Hindawi Limited 2006-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/JBB/2006/18657