iRhom2: An Emerging Adaptor Regulating Immunity and Disease
The rhomboid family are evolutionary conserved intramembrane proteases. Their inactive members, iRhom in <i>Drosophila melanogaster</i> and iRhom1 and iRhom2 in mammals, lack the catalytic center and are hence labelled “inactive” rhomboid family members. In mammals, both iRhoms are invol...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-09-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/21/18/6570 |