iRhom2: An Emerging Adaptor Regulating Immunity and Disease

The rhomboid family are evolutionary conserved intramembrane proteases. Their inactive members, iRhom in <i>Drosophila melanogaster</i> and iRhom1 and iRhom2 in mammals, lack the catalytic center and are hence labelled “inactive” rhomboid family members. In mammals, both iRhoms are invol...

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Bibliographic Details
Main Authors: Mazin A. Al-Salihi, Philipp A. Lang
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/18/6570