TAGCNA: a method to identify significant consensus events of copy number alterations in cancer.

Somatic copy number alteration (CNA) is a common phenomenon in cancer genome. Distinguishing significant consensus events (SCEs) from random background CNAs in a set of subjects has been proven to be a valuable tool to study cancer. In order to identify SCEs with an acceptable type I error rate, bet...

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Bibliographic Details
Main Authors: Xiguo Yuan, Junying Zhang, Liying Yang, Shengli Zhang, Baodi Chen, Yaojun Geng, Yue Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3399811?pdf=render