Prediction of key genes and pathways involved in trastuzumab-resistant gastric cancer

Prediction of key genes and pathways involved in trastuzumab-resistant gastric cancer

Abstract Background Trastuzumab has been prevailingly accepted as a beneficial treatment for gastric cancer (GC) by targeting human epidermal growth factor receptor 2 (HER2)-positive. However, the therapeutic resistance of trastuzumab remains a major obstacle, restricting the therapeutic efficacy. T...

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Bibliographic Details
Main Authors: Chaoran Yu, Pei Xue, Luyang Zhang, Ruijun Pan, Zhenhao Cai, Zirui He, Jing Sun, Minhua Zheng
Format: Article
Language:English
Published: BMC 2018-08-01
Series:World Journal of Surgical Oncology
Subjects:
Differentially expressed genes
Gene ontology
KEGG pathway
Gastric cancer
Trastuzumab
Resistance
Online Access:http://link.springer.com/article/10.1186/s12957-018-1475-6

Internet

http://link.springer.com/article/10.1186/s12957-018-1475-6

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