Flavopereirine—An Alkaloid Derived from <i>Geissospermum vellosii</i>—Presents Leishmanicidal Activity In Vitro

Flavopereirine—An Alkaloid Derived from <i>Geissospermum vellosii</i>—Presents Leishmanicidal Activity In Vitro

Chemotherapy is limited in the treatment of leishmaniasis due to the toxic effects of drugs, low efficacy of alternative treatments, and resistance of the parasite. This work assesses the in vitro activity of flavopereirine on promastigote cultures of <i>Leishmania amazonensis</i>. In ad...

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Bibliographic Details
Main Authors: João Victor da Silva e Silva, Helliton Patrick Cordovil Brigido, Kelly Cristina Oliveira de Albuquerque, Josiwander Miranda Carvalho, Jordano Ferreira Reis, Lara Vinhal Faria, Márlia Regina Coelho-Ferreira, Fernando Tobias Silveira, Agnaldo da Silva Carneiro, Sandro Percário, Andrey Moacir do Rosário Marinho, Maria Fâni Dolabela
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Molecules
Subjects:
leishmania
<i>Geissospermum vellosii</i>
apocynaceae
oligopeptidase B
flavopereirine
medicinal chemistry
in silico modeling
Online Access:https://www.mdpi.com/1420-3049/24/4/785

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https://www.mdpi.com/1420-3049/24/4/785

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