Synthesis and Biological Activity of trans-Tiliroside Derivatives as Potent Anti-Diabetic Agents

A set of novel trans-tiliroside derivatives were synthesized. The structures of the derivatives were identified by their IR, 1H-NMR, and MS spectra analysis. Their anti-diabetic activities were evaluated on the insulin resistant (IR) HepG2 cell model. As a result, compounds 7a, 7c, 7h, and trans-til...

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Bibliographic Details
Main Authors: Yi Liu, Hongwan Chu, Hongquan Duan, Yujin Zhu, Yanjun Zhang
Format: Article
Language:English
Published: MDPI AG 2010-12-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/15/12/9174/