rDNA Copy Number Variants Are Frequent Passenger Mutations in Saccharomyces cerevisiae Deletion Collections and de Novo Transformants

rDNA Copy Number Variants Are Frequent Passenger Mutations in Saccharomyces cerevisiae Deletion Collections and de Novo Transformants

The Saccharomyces cerevisiae ribosomal DNA (rDNA) locus is known to exhibit greater instability relative to the rest of the genome. However, wild-type cells preferentially maintain a stable number of rDNA copies, suggesting underlying genetic control of the size of this locus. We performed a screen...

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Bibliographic Details
Main Authors: Elizabeth X. Kwan, Xiaobin S. Wang, Haley M. Amemiya, Bonita J. Brewer, M. K. Raghuraman
Format: Article
Language:English
Published: Oxford University Press 2016-09-01
Series:G3: Genes, Genomes, Genetics
Subjects:
rDNA
CNV
lithium
transformation
Saccharomyces cerevisiae
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.030296

Internet

http://g3journal.org/lookup/doi/10.1534/g3.116.030296

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