Targeting Glycolysis with Epigallocatechin-3-Gallate Enhances the Efficacy of Chemotherapeutics in Pancreatic Cancer Cells and Xenografts

Pancreatic cancer is a complex disease, in need of new therapeutic approaches. In this study, we explored the effect and mechanism of action of epigallocatechin-3-gallate (EGCG), a major polyphenol in green tea, alone and in combination with current chemotherapeutics on pancreatic cancer cell growth...

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Bibliographic Details
Main Authors: Ran Wei, Robert M. Hackman, Yuefei Wang, Gerardo G. Mackenzie
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Cancers
Subjects:
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Online Access:https://www.mdpi.com/2072-6694/11/10/1496