Association of SNPs in EGR3 and ARC with Schizophrenia Supports a Biological Pathway for Schizophrenia Risk.

We have previously hypothesized a biological pathway of activity-dependent synaptic plasticity proteins that addresses the dual genetic and environmental contributions to schizophrenia. Accordingly, variations in the immediate early gene EGR3, and its target ARC, should influence schizophrenia susce...

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Main Authors: Matthew J Huentelman, Leela Muppana, Jason J Corneveaux, Valentin Dinu, Jeremy J Pruzin, Rebecca Reiman, Cassie N Borish, Matt De Both, Amber Ahmed, Alexandre Todorov, C Robert Cloninger, Rui Zhang, Jie Ma, Amelia L Gallitano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4608790?pdf=render