Environmental acidification drives S. pyogenes pilus expression and microcolony formation on epithelial cells in a FCT-dependent manner.

Group A Streptococcus (GAS, Streptococcus pyogenes) is a gram-positive human pathogen responsible for a diverse variety of diseases, including pharyngitis, skin infections, invasive necrotizing fasciitis and autoimmune sequelae. We have recently shown that GAS cell adhesion and biofilm formation is...

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Bibliographic Details
Main Authors: Andrea G O Manetti, Thomas Köller, Marco Becherelli, Scilla Buccato, Bernd Kreikemeyer, Andreas Podbielski, Guido Grandi, Immaculada Margarit
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21079780/pdf/?tool=EBI