Dermal fibroblast-like cells reprogrammed directly from adipocytes in mouse

Abstract In deep burns, early wound closure is important for healing, and skin grafting is mainly used for wound closure. However, it is difficult to achieve early wound closure in extensive total body surface area deep burns due to the lack of donor sites. Dermal fibroblasts, responsible for dermis...

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Bibliographic Details
Main Authors: Mitsunobu Toyosaki, Koichiro Homma, Sayuri Suzuki, Naoto Muraoka, Hisayuki Hashimoto, Naoki Goshima, Masaki Ieda, Junichi Sasaki
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-78523-8